Design and engineering of whole‐cell biocatalyst for efficient synthesis of (R)‐citronellal

Bioproduction of optical pure (R)‐citronellal from (E/Z)‐citral at high substrate loading remains challenging. Low catalytic efficiency of (R)‐stereoselective ene reductases towards crude citral mixture is one of the major bottlenecks. Herein, a structure‐based engineering strategy was adopted to en...

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Detalles Bibliográficos
Autores principales: Zhang, Baoqi, Du, Han, Zheng, Yanqiu, Sun, Jiale, Shen, Yu, Lin, Jinping, Wei, Dongzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Engineering Biology and Synthetic Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049607/
https://www.ncbi.nlm.nih.gov/pubmed/34729922
http://dx.doi.org/10.1111/1751-7915.13958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049607/
https://www.ncbi.nlm.nih.gov/pubmed/34729922
http://dx.doi.org/10.1111/1751-7915.13958

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