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Design and engineering of whole‐cell biocatalyst for efficient synthesis of (R)‐citronellal
Bioproduction of optical pure (R)‐citronellal from (E/Z)‐citral at high substrate loading remains challenging. Low catalytic efficiency of (R)‐stereoselective ene reductases towards crude citral mixture is one of the major bottlenecks. Herein, a structure‐based engineering strategy was adopted to en...
Autores principales: | Zhang, Baoqi, Du, Han, Zheng, Yanqiu, Sun, Jiale, Shen, Yu, Lin, Jinping, Wei, Dongzhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049607/ https://www.ncbi.nlm.nih.gov/pubmed/34729922 http://dx.doi.org/10.1111/1751-7915.13958 |
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