Deletion of glyceraldehyde‐3‐phosphate dehydrogenase (gapN) in Clostridium saccharoperbutylacetonicum N1‐4(HMT) using CLEAVE™ increases the ATP pool and accelerates solvent production

The development and advent of mutagenesis tools for solventogenic clostridial species in recent years has allowed for the increased refinement of industrially relevant strains. In this study we have utilised CLEAVE™, a CRISPR/Cas genome editing system developed by Green Biologics Ltd., to engineer a...

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Detalles Bibliográficos
Autores principales: Monaghan, Taylor I., Baker, Joseph A., Krabben, Preben, Davies, E. Timothy, Jenkinson, Elizabeth R., Goodhead, Ian B., Robinson, Gary K., Shepherd, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Engineering Biology and Synthetic Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049615/
https://www.ncbi.nlm.nih.gov/pubmed/34927803
http://dx.doi.org/10.1111/1751-7915.13990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049615/
https://www.ncbi.nlm.nih.gov/pubmed/34927803
http://dx.doi.org/10.1111/1751-7915.13990

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