Multiplying the heterologous production of spinosad through tandem amplification of its biosynthetic gene cluster in Streptomyces coelicolor

Heterologous expression of the biosynthetic gene cluster (BGC) is important for studying the microbial natural products (NPs), especially for those kept in silent or poorly expressed in their original strains. Here, we cloned the spinosad BGC through the Cas9‐Assisted Targeting of Chromosome segment...

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Detalles Bibliográficos
Autores principales: Li, Hong, Pan, Yuanyuan, Liu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Engineering Biology and Synthetic Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049625/
https://www.ncbi.nlm.nih.gov/pubmed/34796664
http://dx.doi.org/10.1111/1751-7915.13965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049625/
https://www.ncbi.nlm.nih.gov/pubmed/34796664
http://dx.doi.org/10.1111/1751-7915.13965

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