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Simple and efficient synthesis of bicyclic enol-carbamates: access to brabantamides and their analogues

A novel synthetic approach towards the formation of the unusual bicyclic enol-carbamates, as found in brabantamides A–C, is reported. The bicyclic oxazolidinone framework was obtained in very good yield and with high E/Z selectivity from a readily available β-ketoester under mild reaction conditions...

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Detalles Bibliográficos
Autores principales: Záborský, Ondrej, Petrovičová, Ľudmila, Doháňošová, Jana, Moncol, Ján, Fischer, Róbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049743/
https://www.ncbi.nlm.nih.gov/pubmed/35493865
http://dx.doi.org/10.1039/d0ra00796j