Protodioscin Induces Mitochondrial Apoptosis of Human Hepatocellular Carcinoma Cells Through Eliciting ER Stress-Mediated IP3R Targeting Mfn1/Bak Expression

OBJECTIVE: Protodioscin (PD), a steroidal saponin, has a diverse pharmacological activity including neuroprotection, male fertility improvement, and cytotoxicity against various cancers cell lines of different origins. However, the effect of PD on hepatocellular carcinoma (HCC) is still unclear. MET...

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Detalles Bibliográficos
Autores principales: Yu, Chen-Lin, Lee, Hsiang-Lin, Yang, Shun-Fa, Wang, Shih-Wei, Lin, Ching-Pin, Hsieh, Yi-Hsien, Chiou, Hui-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049873/
https://www.ncbi.nlm.nih.gov/pubmed/35496076
http://dx.doi.org/10.2147/JHC.S355027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049873/
https://www.ncbi.nlm.nih.gov/pubmed/35496076
http://dx.doi.org/10.2147/JHC.S355027

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