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One-pot copper-catalyzed three-component reaction: a modular approach to functionalized 2-quinolones

A copper-catalyzed three-component annulation for the synthesis of functionalized 2-quinolones was developed. Three reactions including an S(N)2, a Knoevenagel, and finally C–N bond formation are involved in the designed cascade reaction using 2-bromoacylarenes, 2-iodoacetamide, and nucleophiles as...

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Detalles Bibliográficos
Autores principales: Kim, Ah Reum, Lim, Hee Nam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049946/
https://www.ncbi.nlm.nih.gov/pubmed/35492152
http://dx.doi.org/10.1039/d0ra01352h