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Population Pharmacokinetics of Intravenous Acyclovir in Oncologic Pediatric Patients

Background: Acyclovir represents the first-line prophylaxis and therapy for herpes virus infections. However, its pharmacokinetics in children exposes them to the risk of ineffective or toxic concentrations. The study was aimed at investigating the population pharmacokinetics (POP/PK) of intravenous...

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Detalles Bibliográficos
Autores principales: Maximova, Natalia, Nisticò, Daniela, Luci, Giacomo, Simeone, Roberto, Piscianz, Elisa, Segat, Ludovica, Barbi, Egidio, Di Paolo, Antonello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050193/
https://www.ncbi.nlm.nih.gov/pubmed/35496277
http://dx.doi.org/10.3389/fphar.2022.865871