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A novel strategy for the characterization of glaucocalyxin A metabolites in vivo and in vitro by UHPLC-Q-TOF-MS based on DDA and DIA data acquisitions

Glaucocalyxin A (GLA) belongs to the natural ent-kauranoid diterpenoids family with antitumor, antifibrotic, anticoagulative, antioxidant, and anti-AD effects. In this study, ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS) system w...

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Detalles Bibliográficos
Autores principales: Sun, Wenjing, Jin, Yiran, Guan, Shuai, Yang, Mengxin, Zhang, Miaoting, Hou, Jiali, Du, Yingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050391/
https://www.ncbi.nlm.nih.gov/pubmed/35492945
http://dx.doi.org/10.1039/c9ra06830a