Development and Validation of a High-Throughput Screen for Inhibitors of SARS CoV and Its Application in Screening of a 100,000-Compound Library

The authors have developed a high-throughput screen (HTS) that allows for the identification of potential inhibitors of the severe acute respiratory syndrome coronavirus (SARS CoV) from large compound libraries. The luminescent-based assay measures the inhibition of SARS CoV–induced cytopathic effec...

Descripción completa

Detalles Bibliográficos
Autores principales: Severson, William E., Shindo, Nice, Sosa, Mindy, Fletcher, III, Thomas, White, E. Lucile, Ananthan, Subramaniam, Jonsson, Colleen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Laboratory Automation and Screening. Published by Elsevier Inc. 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050465/
https://www.ncbi.nlm.nih.gov/pubmed/17200104
http://dx.doi.org/10.1177/1087057106296688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050465/
https://www.ncbi.nlm.nih.gov/pubmed/17200104
http://dx.doi.org/10.1177/1087057106296688

Ejemplares similares