Mannosylated hemagglutinin peptides bind cyanovirin-N independent of disulfide-bonds in complementary binding sites

Cyanovirin-N (CV-N) has been shown to reveal broad neutralizing activity against human immunodeficiency virus (HIV) and to specifically bind Manα(1→2)Manα units exposed on various glycoproteins of enveloped viruses, such as influenza hemagglutinin (HA) and Ebola glycoprotein. Chemically synthesized...

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Detalles Bibliográficos
Autores principales: Schilling, Philipp E., Kontaxis, Georg, Dragosits, Martin, Schiestl, Robert H., Becker, Christian F. W., Maier, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050506/
https://www.ncbi.nlm.nih.gov/pubmed/35495330
http://dx.doi.org/10.1039/d0ra01128b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050506/
https://www.ncbi.nlm.nih.gov/pubmed/35495330
http://dx.doi.org/10.1039/d0ra01128b

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