Cargando…

Imbalanced basal ganglia connectivity is associated with motor deficits and apathy in Huntington’s disease

The gating of movement depends on activity within the cortico-striato-thalamic loops. Within these loops, emerging from the cells of the striatum, run two opponent pathways—the direct and indirect basal ganglia pathways. Both are complex and polysynaptic, but the overall effect of activity within th...

Descripción completa

Detalles Bibliográficos
Autores principales: Nair, Akshay, Razi, Adeel, Gregory, Sarah, Rutledge, Robb B, Rees, Geraint, Tabrizi, Sarah J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050569/
https://www.ncbi.nlm.nih.gov/pubmed/34633421
http://dx.doi.org/10.1093/brain/awab367