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Imbalanced basal ganglia connectivity is associated with motor deficits and apathy in Huntington’s disease
The gating of movement depends on activity within the cortico-striato-thalamic loops. Within these loops, emerging from the cells of the striatum, run two opponent pathways—the direct and indirect basal ganglia pathways. Both are complex and polysynaptic, but the overall effect of activity within th...
Autores principales: | Nair, Akshay, Razi, Adeel, Gregory, Sarah, Rutledge, Robb B, Rees, Geraint, Tabrizi, Sarah J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050569/ https://www.ncbi.nlm.nih.gov/pubmed/34633421 http://dx.doi.org/10.1093/brain/awab367 |
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