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Ameliorating amyloid aggregation through osmolytes as a probable therapeutic molecule against Alzheimer's disease and type 2 diabetes
Large numbers of neurological and metabolic disorders occurring in humans are induced by the aberrant growth of aggregated or misfolded proteins. Alzheimer's disease (AD) and type 2 diabetes (T2D) are two of the most prevalent disorders that lead to toxic protofibrils of amyloid beta (Aβ) and h...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050657/ https://www.ncbi.nlm.nih.gov/pubmed/35497581 http://dx.doi.org/10.1039/d0ra00429d |