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Ameliorating amyloid aggregation through osmolytes as a probable therapeutic molecule against Alzheimer's disease and type 2 diabetes

Large numbers of neurological and metabolic disorders occurring in humans are induced by the aberrant growth of aggregated or misfolded proteins. Alzheimer's disease (AD) and type 2 diabetes (T2D) are two of the most prevalent disorders that lead to toxic protofibrils of amyloid beta (Aβ) and h...

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Detalles Bibliográficos
Autores principales: Kumari, Anchala, Somvanshi, Pallavi, Grover, Abhinav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050657/
https://www.ncbi.nlm.nih.gov/pubmed/35497581
http://dx.doi.org/10.1039/d0ra00429d