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Structure-based inhibitor design for reshaping bacterial morphology

The spiral shape of intestinal pathogen Campylobacter jejuni is critical for invasion of intestinal mucosa epithelial cells. Insofar as this cell morphology plays a role in the pathology of C. jejuni infection, its restructuring by pharmacological intervention could be an unexplored means to prevent...

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Detalles Bibliográficos
Autores principales: Choi, Yuri, Park, Ji Su, Kim, Jinshil, Min, Kyungjin, Mahasenan, Kiran, Kim, Choon, Yoon, Hye-Jin, Lim, Sewon, Cheon, Dae Hee, Lee, Yan, Ryu, Sangryeol, Mobashery, Shahriar, Kim, B. Moon, Lee, Hyung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050674/
https://www.ncbi.nlm.nih.gov/pubmed/35484224
http://dx.doi.org/10.1038/s42003-022-03355-3