Cu/TEMPO catalyzed dehydrogenative 1,3-dipolar cycloaddition in the synthesis of spirooxindoles as potential antidiabetic agents

A series of spiro-[indoline-3,3′-pyrrolizin/pyrrolidin]-2-ones, 4, 5 and 6 were synthesized in a sequential manner from Cu–TEMPO catalyzed dehydrogenation of alkylated ketones, 1 followed by 1,3-dipolar cycloaddition of azomethine ylides via decarboxylative condensation of isatin, 2 and l-proline/sa...

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Detalles Bibliográficos
Autores principales: Teja, Chitrala, Babu, Spoorthy N., Noor, Ayesha, Daniel, J. Arul, Devi, S. Asha, Nawaz Khan, Fazlur Rahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050786/
https://www.ncbi.nlm.nih.gov/pubmed/35497611
http://dx.doi.org/10.1039/d0ra01553a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050786/
https://www.ncbi.nlm.nih.gov/pubmed/35497611
http://dx.doi.org/10.1039/d0ra01553a

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