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Seeking potent anti-tubercular agents: design and synthesis of substituted-N-(6-(4-(pyrazine-2-carbonyl)piperazine/homopiperazine-1-yl)pyridin-3-yl)benzamide derivatives as anti-tubercular agents

Pyrazinamide is an important first-line drug used in shortening TB therapy. In our current work, a series of novel substituted-N-(6-(4-(pyrazine-2-carbonyl)piperazine/homopiperazine-1-yl)pyridin-3-yl)benzamide derivatives were designed, synthesized, and evaluated for their anti-tubercular activity a...

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Detalles Bibliográficos
Autores principales: Srinivasarao, Singireddi, Nandikolla, Adinarayana, Suresh, Amaroju, Calster, Kevin Van, De Voogt, Linda, Cappoen, Davie, Ghosh, Balaram, Aggarwal, Himanshu, Murugesan, Sankaranarayanan, Chandra Sekhar, Kondapalli Venkata Gowri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050811/
https://www.ncbi.nlm.nih.gov/pubmed/35497605
http://dx.doi.org/10.1039/d0ra01348j