Macrophages Use Apoptotic Cell-Derived Methionine and DNMT3A During Efferocytosis to Promote Tissue Resolution

Efferocytosis, the clearance of apoptotic cells (ACs) by macrophages, is critical for tissue resolution, with defects driving many diseases. Mechanisms of efferocytosis-mediated resolution are incompletely understood. Here, we show that AC-derived methionine regulates resolution through epigenetic r...

Descripción completa

Detalles Bibliográficos
Autores principales: Ampomah, Patrick B., Cai, Bishuang, Sukka, Santosh R., Gerlach, Brennan D., Yurdagul, Arif, Wang, Xiaobo, Kuriakose, George, Darville, Lancia N.F., Sun, Yan, Sidoli, Simone, Koomen, John M., Tall, Alan R., Tabas, Ira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050866/
https://www.ncbi.nlm.nih.gov/pubmed/35361955
http://dx.doi.org/10.1038/s42255-022-00551-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050866/
https://www.ncbi.nlm.nih.gov/pubmed/35361955
http://dx.doi.org/10.1038/s42255-022-00551-7

Ejemplares similares