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Macrophages Use Apoptotic Cell-Derived Methionine and DNMT3A During Efferocytosis to Promote Tissue Resolution
Efferocytosis, the clearance of apoptotic cells (ACs) by macrophages, is critical for tissue resolution, with defects driving many diseases. Mechanisms of efferocytosis-mediated resolution are incompletely understood. Here, we show that AC-derived methionine regulates resolution through epigenetic r...
Autores principales: | Ampomah, Patrick B., Cai, Bishuang, Sukka, Santosh R., Gerlach, Brennan D., Yurdagul, Arif, Wang, Xiaobo, Kuriakose, George, Darville, Lancia N.F., Sun, Yan, Sidoli, Simone, Koomen, John M., Tall, Alan R., Tabas, Ira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050866/ https://www.ncbi.nlm.nih.gov/pubmed/35361955 http://dx.doi.org/10.1038/s42255-022-00551-7 |
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