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6,N(2)-Diaryl-1,3,5-triazine-2,4-diamines: synthesis, antiproliferative activity and 3D-QSAR modeling

A library of 126 compounds with a 6,N(2)-diaryl-1,3,5-triazine-2,4-diamine scaffold was prepared using a one-pot, microwave-assisted method from readily available cyanoguanidine, aromatic aldehydes and arylamines. The three-component condensation of these reagents in the presence of hydrochloric aci...

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Detalles Bibliográficos
Autores principales: Junaid, Ahmad, Lim, Felicia Phei Lin, Chuah, Lay Hong, Dolzhenko, Anton V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050923/
https://www.ncbi.nlm.nih.gov/pubmed/35497593
http://dx.doi.org/10.1039/d0ra00643b