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Upregulation of DGCR8, a Candidate Predisposing to Schizophrenia in Han Chinese, Contributes to Phenotypic Deficits and Neuronal Migration Delay

DiGeorge Syndrome Critical Region Gene 8 (DGCR8) is a key component of the microprocessor complex governing the maturation of most microRNAs, some of which participate in schizophrenia and neural development. Previous studies have found that the 22q11.2 locus, containing DGCR8, confers a risk of sch...

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Detalles Bibliográficos
Autores principales: Bi, Yan, Chen, Shiqing, Shen, Qi, Guo, Zhenming, Ren, Decheng, Yuan, Fan, Niu, Weibo, Ji, Lei, Liu, Liangjie, Han, Ke, Yu, Tao, Yang, Fengping, Wu, Xi, Wang, Lu, Li, Xingwang, Yu, Shunying, Xu, Yifeng, He, Lin, Shi, Yi, Zhang, Jing, Li, Weidong, He, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051063/
https://www.ncbi.nlm.nih.gov/pubmed/35492695
http://dx.doi.org/10.3389/fpsyt.2022.873873