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A 2-Gene Signature Related to Interferon-Gamma Predicts Prognosis and Responsiveness to Immune Checkpoint Blockade of Glioma

BACKGROUND: Gliomas represent the most common and aggressive brain malignancy. Interferon-gamma (IFNG) is a potent inducer of immune response, developing IFNG-related gene signature may promote the diagnosis and treatment of this disease. METHODS: Bulk tumor and single-cell mRNA-seq datasets of glio...

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Detalles Bibliográficos
Autores principales: Li, Yongzhe, Ji, Hang, Gao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051065/
https://www.ncbi.nlm.nih.gov/pubmed/35492352
http://dx.doi.org/10.3389/fmed.2022.846847