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Prenatal GABAB Receptor Agonist Administration Corrects the Inheritance of Autism-Like Core Behaviors in Offspring of Mice Prenatally Exposed to Valproic Acid

This study was performed to evaluate the effects of prenatal baclofen (a GABAB receptor agonist) treatment on the inheritance of autism-like behaviors in valproic acid (VPA)-exposed mice. VPA model mice (first generation, F1) that were prenatally exposed to VPA exhibited robust core autism-like beha...

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Detalles Bibliográficos
Autores principales: Jiang, Shucai, He, Maotao, Xiao, Lifei, Sun, Yu, Ding, Jiangwei, Li, Wenchao, Guo, Baorui, Wang, Lei, Wang, Yangyang, Gao, Caibin, Sun, Tao, Wang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051083/
https://www.ncbi.nlm.nih.gov/pubmed/35492716
http://dx.doi.org/10.3389/fpsyt.2022.835993