Cargando…

Prenatal GABAB Receptor Agonist Administration Corrects the Inheritance of Autism-Like Core Behaviors in Offspring of Mice Prenatally Exposed to Valproic Acid

This study was performed to evaluate the effects of prenatal baclofen (a GABAB receptor agonist) treatment on the inheritance of autism-like behaviors in valproic acid (VPA)-exposed mice. VPA model mice (first generation, F1) that were prenatally exposed to VPA exhibited robust core autism-like beha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Shucai, He, Maotao, Xiao, Lifei, Sun, Yu, Ding, Jiangwei, Li, Wenchao, Guo, Baorui, Wang, Lei, Wang, Yangyang, Gao, Caibin, Sun, Tao, Wang, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Psychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051083/ https://www.ncbi.nlm.nih.gov/pubmed/35492716 http://dx.doi.org/10.3389/fpsyt.2022.835993

Ejemplares similares

The GABAB receptor agonist STX209 reverses the autism-like behaviour in an animal model of autism induced by prenatal exposure to valproic acid
por: Jiang, Shucai, et al.
Publicado: (2022)

Continuous high-frequency deep brain stimulation of the anterior insula modulates autism-like behavior in a valproic acid-induced rat model
por: Xiao, Lifei, et al.
Publicado: (2022)

Glucagon-Like Peptide-1 Agonist Exendin-4 Facilitates the Extinction of Cocaine-Induced Condition Place Preference
por: Zhu, Changliang, et al.
Publicado: (2021)

Pentylenetetrazole-induced seizures in developing rats prenatally exposed to valproic acid
por: Puig-Lagunes, Angel A., et al.
Publicado: (2016)

Gastrointestinal Tract Abnormalities Induced by Prenatal Valproic Acid Exposure in Rat Offspring
por: Kim, Ji-Woon, et al.
Publicado: (2013)

Phosphoproteomic profiling of the hippocampus of offspring rats exposed to prenatal stress
por: Li, Qinghong, et al.
Publicado: (2021)

Developmental disruption of amygdala transcriptome and socioemotional behavior in rats exposed to valproic acid prenatally
por: Barrett, Catherine E., et al.
Publicado: (2017)

Prenatal maternal stress and offspring aggressive behavior: Intergenerational and transgenerational inheritance
por: Mbiydzenyuy, Ngala Elvis, et al.
Publicado: (2022)

Gender Differences in the Outcome of Offspring Prenatally Exposed to Drugs of Abuse
por: Traccis, Francesco, et al.
Publicado: (2020)

Transcriptome Analysis in Hippocampus of Rats Prenatally Exposed to Valproic Acid and Effects of Intranasal Treatment of Oxytocin
por: Matsuo, Kazuya, et al.
Publicado: (2022)

Influence of Panax ginseng on the offspring of adult rats exposed to prenatal stress
por: KIM, YOUNG OCK, et al.
Publicado: (2015)

Beneficial effects of co-treatment with dextromethorphan on prenatally methadone-exposed offspring
por: Chiang, Yao-Chang, et al.
Publicado: (2015)

Hypo-Hydroxymethylation of Nobox is Associated with Ovarian Dysfunction in Rat Offspring Exposed to Prenatal Hypoxia
por: Yao, Changfang, et al.
Publicado: (2022)

Transcriptomic analysis in the striatum reveals the involvement of Nurr1 in the social behavior of prenatally valproic acid-exposed male mice
por: Kim, Hyunju, et al.
Publicado: (2022)

The links between prenatal stress and offspring development and psychopathology: disentangling environmental and inherited influences
por: Rice, F., et al.
Publicado: (2010)

Consequences of prenatal exposure to valproic acid in the socially monogamous prairie voles
por: Sailer, L., et al.
Publicado: (2019)

Intron 4 Containing Novel GABAB1 Isoforms Impair GABAB Receptor Function
por: Lee, Changhoon, et al.
Publicado: (2010)

Juvenile handling rescues autism-related effects of prenatal exposure to valproic acid
por: Seiffe, Araceli, et al.
Publicado: (2022)

Effects of Atomoxetine on Hyper-Locomotive Activity of the Prenatally Valproate-Exposed Rat Offspring
por: Choi, Chang Soon, et al.
Publicado: (2014)

The transgenerational inheritance of autism-like phenotypes in mice exposed to valproic acid during pregnancy
por: Choi, Chang Soon, et al.
Publicado: (2016)

Suppression of NMDA receptor function in mice prenatally exposed to valproic acid improves social deficits and repetitive behaviors
por: Kang, Jaeseung, et al.
Publicado: (2015)

Targeting anandamide metabolism rescues core and associated autistic-like symptoms in rats prenatally exposed to valproic acid
por: Servadio, M, et al.
Publicado: (2016)

Mice prenatally exposed to valproic acid do not show autism-related disorders when fed with polyunsaturated fatty acid-enriched diets
por: Turpin, Valentine, et al.
Publicado: (2023)

Astaxanthin ameliorates prenatal LPS-exposed behavioral deficits and oxidative stress in adult offspring
por: Al-Amin, Md. Mamun, et al.
Publicado: (2016)

Increasing Endocannabinoid Tone Alters Anxiety-Like and Stress Coping Behaviour in Female Rats Prenatally Exposed to Valproic Acid
por: Thornton, Aoife M., et al.
Publicado: (2021)

Group I and group II metabotropic glutamate receptors are upregulated in the synapses of infant rats prenatally exposed to valproic acid
por: D’Antoni, Simona, et al.
Publicado: (2023)

Inherited risk plus prenatal insult caused malignant dysfunction in mesenteric arteries in adolescent SHR offspring
por: Zhong, Yuan, et al.
Publicado: (2019)

Inhibition of Valproic Acid-Induced Prenatal Developmental Abnormalities with Antioxidants in Rats
por: Saeed, Mamoona, et al.
Publicado: (2020)

Prenatal valproic acid-induced autism marmoset model exhibits higher salivary cortisol levels
por: Nakamura, Madoka, et al.
Publicado: (2022)

Imprinting of cerebral cytochrome P450s in offsprings prenatally exposed to cypermethrin augments toxicity on rechallenge
por: Singh, Anshuman, et al.
Publicado: (2016)

Neuroinflammatory and Behavioral Outcomes Measured in Adult Offspring of Mice Exposed Prenatally to E-Cigarette Aerosols
por: Church, Jamie S., et al.
Publicado: (2020)

Prenatal Maternal Stress Exacerbates Experimental Colitis of Offspring in Adulthood
por: Sun, Yue, et al.
Publicado: (2021)

Effects of Glucagon-Like Peptide-1 Receptor Agonist Exendin-4 on the Reinstatement of Cocaine-Mediated Conditioned Place Preference in Mice
por: Zhu, Changliang, et al.
Publicado: (2022)

Mouse hippocampal GABAB1 but not GABAB2 subunit-containing receptor complex levels are paralleling retrieval in the multiple-T-maze
por: Falsafi, Soheil K., et al.
Publicado: (2015)

Prenatal Alcohol Exposure and the Risk of Depression in Offspring: a Meta-Analysis
por: Zhang, Xiaoming, et al.
Publicado: (2022)

Effects of an H3R Antagonist on the Animal Model of Autism Induced by Prenatal Exposure to Valproic Acid
por: Baronio, Diego, et al.
Publicado: (2015)

Cariprazine alleviates core behavioral deficits in the prenatal valproic acid exposure model of autism spectrum disorder
por: Román, Viktor, et al.
Publicado: (2021)

The Role of GABAB Receptors in Morphine Self-Administration
por: Ramshini, Effat, et al.
Publicado: (2013)

Regulating hippocampal hyperexcitability through GABAB Receptors
por: Lang, Min, et al.
Publicado: (2014)

Prenatal Hypoxia Induced Dysfunction in Cerebral Arteries of Offspring Rats
por: Tang, Jiaqi, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_i8uhn1l8f8hecji7drclfn5dsm