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Crystal structures and insights into precursor tRNA 5’-end processing by prokaryotic minimal protein-only RNase P
Besides the canonical RNA-based RNase P, pre-tRNA 5’-end processing can also be catalyzed by protein-only RNase P (PRORP). To date, various PRORPs have been discovered, but the basis underlying substrate binding and cleavage by HARPs (homolog of Aquifex RNase P) remains elusive. Here, we report stru...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051087/ https://www.ncbi.nlm.nih.gov/pubmed/35484139 http://dx.doi.org/10.1038/s41467-022-30072-6 |