Crystal structures and insights into precursor tRNA 5’-end processing by prokaryotic minimal protein-only RNase P

Besides the canonical RNA-based RNase P, pre-tRNA 5’-end processing can also be catalyzed by protein-only RNase P (PRORP). To date, various PRORPs have been discovered, but the basis underlying substrate binding and cleavage by HARPs (homolog of Aquifex RNase P) remains elusive. Here, we report stru...

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Detalles Bibliográficos
Autores principales: Li, Yangyang, Su, Shichen, Gao, Yanqing, Lu, Guoliang, Liu, Hehua, Chen, Xi, Shao, Zhiwei, Zhang, Yixi, Shao, Qiyuan, Zhao, Xin, Yang, Jie, Cao, Chulei, Lin, Jinzhong, Ma, Jinbiao, Gan, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051087/
https://www.ncbi.nlm.nih.gov/pubmed/35484139
http://dx.doi.org/10.1038/s41467-022-30072-6

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