MyD88 in hepatic stellate cells enhances liver fibrosis via promoting macrophage M1 polarization

During liver fibrosis, quiescent HSCs (qHSCs) are activated to become activated HSCs (aHSCs)/myofibroblasts. The signal adapter MyD88, an essential component of TLR signaling, plays an important role in liver fibrosis. However, far less is known about the specific effects of MyD88 signaling in both...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Liu, Yu, Chen, Haiqiang, Yuan, Qi, Wang, Jinyan, Niu, Meng, Hou, Lingling, Gu, Jianchun, Zhang, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051099/
https://www.ncbi.nlm.nih.gov/pubmed/35484116
http://dx.doi.org/10.1038/s41419-022-04802-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051099/
https://www.ncbi.nlm.nih.gov/pubmed/35484116
http://dx.doi.org/10.1038/s41419-022-04802-z

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