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Substance P Increases the Excitability of Dorsal Motor Nucleus of the Vagus Nerve via Inhibition of Potassium Channels

Increases in the substance P (SP) concentration in the medial portion of the dorsal motor nucleus of the vagus nerve (mDMV) in the brainstem are closely associated with chemotherapy induced nausea and vomiting (CINV). However, the underlying cellular and molecular mechanisms of action are not well u...

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Detalles Bibliográficos
Autores principales: Yang, Eunhee, Kim, Woojin, Park, Yong Seek, Jin, Young-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051405/
https://www.ncbi.nlm.nih.gov/pubmed/35495038
http://dx.doi.org/10.3389/fnins.2022.867831