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Superior antitumor effect of self-assembly supramolecular paclitaxel nanoparticles

Paclitaxel (Ptx), a microtubule depolymerization inhibitor, is one of the first-line regimens in lung cancer chemotherapy. However, the poor solubility of Ptx, as well as hypersensitivity of the solvent Cremphor EL, severely limits its clinical application. Here we developed a drug-polymer conjugate...

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Detalles Bibliográficos
Autores principales: Yu, Na, Li, Jun, Zhang, Yuan, Ding, Dan, Li, Xiaolin, Xu, Huae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051418/
https://www.ncbi.nlm.nih.gov/pubmed/35492086
http://dx.doi.org/10.1039/d0ra01117g