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Discovery of Novel Drug Candidates for Alzheimer’s Disease by Molecular Network Modeling

To identify the molecular mechanisms and novel therapeutic agents of late-onset Alzheimer’s disease (AD), we performed integrative network analysis using multiple transcriptomic profiles of human brains. With the hypothesis that AD pathology involves the whole cerebrum, we first identified co-expres...

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Detalles Bibliográficos
Autores principales: Zhou, Jiaxin, Li, Qingyong, Wu, Wensi, Zhang, Xiaojun, Zuo, Zhiyi, Lu, Yanan, Zhao, Huiying, Wang, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051440/
https://www.ncbi.nlm.nih.gov/pubmed/35493947
http://dx.doi.org/10.3389/fnagi.2022.850217