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Oral Treatments With the TrkB Ligand Prodrug, R13, Promote Enhanced Axon Regeneration Following Peripheral Nerve Injury

Axon regeneration after peripheral nerve injury is slow and inefficient, leading to generally poor functional recovery. Activity-dependent experimental therapies that increase expression of brain-derived neurotrophic factor (BDNF) and its TrkB receptors enhance regeneration, suggesting that treatmen...

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Detalles Bibliográficos
Autores principales: English, Arthur W., Carrasco, Dario, Hoffman, Dustin, Isaacson, Robin, Kang, Seong Su, Khan, Samia, Liu, Xia, Ye, Keqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051483/
https://www.ncbi.nlm.nih.gov/pubmed/35496909
http://dx.doi.org/10.3389/fncel.2022.857664