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Oral Treatments With the TrkB Ligand Prodrug, R13, Promote Enhanced Axon Regeneration Following Peripheral Nerve Injury
Axon regeneration after peripheral nerve injury is slow and inefficient, leading to generally poor functional recovery. Activity-dependent experimental therapies that increase expression of brain-derived neurotrophic factor (BDNF) and its TrkB receptors enhance regeneration, suggesting that treatmen...
Autores principales: | English, Arthur W., Carrasco, Dario, Hoffman, Dustin, Isaacson, Robin, Kang, Seong Su, Khan, Samia, Liu, Xia, Ye, Keqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051483/ https://www.ncbi.nlm.nih.gov/pubmed/35496909 http://dx.doi.org/10.3389/fncel.2022.857664 |
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