Nitrileimines as an alternative to azides in base-mediated click [3 + 2] cycloaddition with methylene active nitriles

Nitrileimines were implemented in practical click protocols with oxopropanenitriles for the straightforward 5-amino-1H-pyrazole synthesis via 1,3-dipolar cycloaddition. The reaction proceeds at room temperature in a short time with base catalysis and no chromatographic purification. High purity prod...

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Detalles Bibliográficos
Autores principales: Tupychak, Mykola A., Shyyka, Olga Ya., Pokhodylo, Nazariy T., Obushak, Mykola D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051556/
https://www.ncbi.nlm.nih.gov/pubmed/35493004
http://dx.doi.org/10.1039/d0ra01417f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051556/
https://www.ncbi.nlm.nih.gov/pubmed/35493004
http://dx.doi.org/10.1039/d0ra01417f

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