Asymmetric inheritance of RNA toxicity in C. elegans expressing CTG repeats

Nucleotide repeat expansions are a hallmark of over 40 neurodegenerative diseases and cause RNA toxicity and multisystemic symptoms that worsen with age. Through an unclear mechanism, RNA toxicity can trigger severe disease manifestation in infants if the repeats are inherited from their mother. Her...

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Detalles Bibliográficos
Autores principales: Braun, Maya, Shoshani, Shachar, Teixeira, Joana, Mellul Shtern, Anna, Miller, Maya, Granot, Zvi, Fischer, Sylvia E.J., Garcia, Susana M.D. A., Tabach, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051633/
https://www.ncbi.nlm.nih.gov/pubmed/35494247
http://dx.doi.org/10.1016/j.isci.2022.104246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051633/
https://www.ncbi.nlm.nih.gov/pubmed/35494247
http://dx.doi.org/10.1016/j.isci.2022.104246

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