Cargando…
Asymmetric inheritance of RNA toxicity in C. elegans expressing CTG repeats
Nucleotide repeat expansions are a hallmark of over 40 neurodegenerative diseases and cause RNA toxicity and multisystemic symptoms that worsen with age. Through an unclear mechanism, RNA toxicity can trigger severe disease manifestation in infants if the repeats are inherited from their mother. Her...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051633/ https://www.ncbi.nlm.nih.gov/pubmed/35494247 http://dx.doi.org/10.1016/j.isci.2022.104246 |