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Design and synthesis of lipid-mimetic cationic iridium complexes and their liposomal formulation for in vitro and in vivo application in luminescent bioimaging

Two iridium [Ir(N^C)(2)(N^N)](+) complexes with the diimine N^N ligand containing a long polymethylene hydrophobic chain were synthesized and characterized by using NMR and ESI mass-spectrometry: N^N – 2-(1-hexadecyl-1H-imidazol-2-yl)pyridine, N^C – methyl-2-phenylquinoline-4-carboxylate (Ir1) and 2...

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Detalles Bibliográficos
Autores principales: Shakirova, Julia R., Sadeghi, Amir, Koblova, Alla A., Chelushkin, Pavel S., Toropainen, Elisa, Tavakoli, Shirin, Kontturi, Leena-Stiina, Lajunen, Tatu, Tunik, Sergey P., Urtti, Arto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051922/
https://www.ncbi.nlm.nih.gov/pubmed/35498460
http://dx.doi.org/10.1039/d0ra01114b