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Repurposing pantoprazole and haloperidol as efflux pump inhibitors in azole resistant clinical Candida albicans and non-albicans isolates

Candida species have a major role in nosocomial infections leading to high morbidity and mortality. Increased resistance to various antifungals, especially azoles is a significant problem. One of the main mechanisms for azole resistance is the up-regulation of efflux pump genes including CDR1 and MD...

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Detalles Bibliográficos
Autores principales: El-Ganiny, Amira M., Kamel, Hend A., Yossef, Nehal E., Mansour, Basem, El-Baz, Ahmed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051972/
https://www.ncbi.nlm.nih.gov/pubmed/35498219
http://dx.doi.org/10.1016/j.jsps.2022.01.011