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Immune cell infiltration pattern in non-small cell lung cancer PDX models is a model immanent feature and correlates with a distinct molecular and phenotypic make-up

BACKGROUND: The field of cancer immunology is rapidly moving towards innovative therapeutic strategies, resulting in the need for robust and predictive preclinical platforms reflecting the immunological response to cancer. Well characterized preclinical models are essential for the development of pr...

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Detalles Bibliográficos
Autores principales: Oswald, Eva, Bug, Daniel, Grote, Anne, Lashuk, Kanstantsin, Bouteldja, Nassim, Lenhard, Dorothee, Löhr, Anne, Behnke, Anke, Knauff, Volker, Edinger, Anna, Klingner, Kerstin, Gaedicke, Simone, Niedermann, Gabriele, Merhof, Dorit, Feuerhake, Friedrich, Schueler, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052060/
https://www.ncbi.nlm.nih.gov/pubmed/35483746
http://dx.doi.org/10.1136/jitc-2021-004412