Cargando…

Separation and identification of an impurity from the istradefylline intermediate

Istradefylline is a selective adenosine antagonist for the A(2a) receptor, and it is used to treat the Parkinson's disease and improve dyskinesia in the early stage of the Parkinson's disease. An impurity in the istradefylline intermediate A(1) (6-amino-1,3-diethyl-2,4-(1H,3H)-pyrimidinedi...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Haojie, Wang, Yiyun, Wang, Hongyi, Zheng, Zhonghui, Meng, Zihui, Xue, Min, Xu, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052088/
https://www.ncbi.nlm.nih.gov/pubmed/35497116
http://dx.doi.org/10.1039/c9ra09074f