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Separation and identification of an impurity from the istradefylline intermediate
Istradefylline is a selective adenosine antagonist for the A(2a) receptor, and it is used to treat the Parkinson's disease and improve dyskinesia in the early stage of the Parkinson's disease. An impurity in the istradefylline intermediate A(1) (6-amino-1,3-diethyl-2,4-(1H,3H)-pyrimidinedi...
Autores principales: | Xu, Haojie, Wang, Yiyun, Wang, Hongyi, Zheng, Zhonghui, Meng, Zihui, Xue, Min, Xu, Zhibin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052088/ https://www.ncbi.nlm.nih.gov/pubmed/35497116 http://dx.doi.org/10.1039/c9ra09074f |
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