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Strategy to design a smart photocleavable and pH sensitive chitosan based hydrogel through a novel crosslinker: a potential vehicle for controlled drug delivery

We report herein the synthesis of a novel photocleavable crosslinker, 4-formylphenyl 4-((4-formylphenoxy)methyl)-3-nitrobenzoate (CHO–ONB–CHO) and its joining with amine-based polysaccharides, viz. chitosan, resulting in the formation of a dual stimuli-responsive (ONB–chitosan) hydrogel having UV- a...

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Detalles Bibliográficos
Autores principales: Nisar, Safiya, Pandit, Ashiq Hussain, Wang, Li-Fang, Rattan, Sunita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052095/
https://www.ncbi.nlm.nih.gov/pubmed/35497171
http://dx.doi.org/10.1039/c9ra10333c