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Double-edged effects and mechanisms of Zn(2+) microenvironments on osteogenic activity of BMSCs: osteogenic differentiation or apoptosis

Zinc-incorporated biomaterials show promoting effects on osteogenesis; however, excessive zinc ions lead to cytotoxic reactions and also have other adverse effects. Therefore, the double-edged effects of Zn(2+) microenvironments on osteogenesis may become critical issues for new material development...

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Detalles Bibliográficos
Autores principales: Yu, Yiqiang, Liu, Kai, Wen, Zhuo, Liu, Weicai, Zhang, Lei, Su, Jiansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052110/
https://www.ncbi.nlm.nih.gov/pubmed/35497133
http://dx.doi.org/10.1039/d0ra01465f