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Downregulation of the endothelial histone demethylase JMJD3 is associated with neointimal hyperplasia of arteriovenous fistulas in kidney failure
Jumonji domain–containing protein-3 (JMJD3), a histone H3 lysine 27 (H3K27) demethylase, promotes endothelial regeneration, but its function in neointimal hyperplasia (NIH) of arteriovenous fistulas (AVFs) has not been explored. In this study, we examined the contribution of endothelial JMJD3 to NIH...
Autores principales: | Feng, Shaozhen, Peden, Eric K., Guo, Qunying, Lee, Tae Hoon, Li, Qingtian, Yuan, Yuhui, Chen, Changyi, Huang, Fengzhang, Cheng, Jizhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052161/ https://www.ncbi.nlm.nih.gov/pubmed/35278430 http://dx.doi.org/10.1016/j.jbc.2022.101816 |
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