Construction of multi-substituted pyrazoles via potassium carbonate-mediated [3 + 2] cycloaddition of in situ generated nitrile imines with cinnamic aldehydes

A highly efficient potassium carbonate-mediated [3 + 2] cycloaddition reaction of hydrazonoyl chlorides with cinnamic aldehydes to furnish multi-substituted pyrazoles under nontoxic and mild conditions has been developed. A plausible stepwise cycloaddition reaction mechanism is proposed. This protoc...

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Detalles Bibliográficos
Autores principales: Li, Mei-Mei, Huang, Hui, Tian, Wanrong, Pu, Yiru, Zhang, Chaozheng, Yang, Jirui, Ren, Qing, Tao, Feiyan, Deng, Yun, Lu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052213/
https://www.ncbi.nlm.nih.gov/pubmed/35497007
http://dx.doi.org/10.1039/d2ra00331g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052213/
https://www.ncbi.nlm.nih.gov/pubmed/35497007
http://dx.doi.org/10.1039/d2ra00331g

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