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Substrate controlled, regioselective carbopalladation for the one-pot synthesis of C4-substituted tetrahydroisoquinoline analogues

6-Exo-trig cyclization reaction through regioselective carbopalladation was demonstrated with N-(2-halobenzyl)-N-allylamines to furnish the corresponding C4-substituted tetrahydroisoquinoline derivatives. The scope of the reaction was extended to the synthesis of C4-quaternary tetrahydroisoquinoline...

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Detalles Bibliográficos
Autores principales: Krishna Reddy, Singarajanahalli Mundarinti, Suresh, Pavithira, Thamotharan, Subbiah, Nanubolu, Jagadeesh Babu, Suresh, Surisetti, Selva Ganesan, Subramaniapillai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052373/
https://www.ncbi.nlm.nih.gov/pubmed/35493635
http://dx.doi.org/10.1039/d0ra01539c