Introducing chirality in halogenated 3-arylsydnones and their corresponding 1-arylpyrazoles obtained by 1,3-dipolar cycloaddition

New 1-arylpyrazoles substituted with halogen atoms (Br, I) were synthesized from the corresponding sydnones by 1,3-dipolar cycloaddition. By introduction of a prochiral group such as isopropyl, in the ortho position of the benzene ring, in the starting phenylglycine 1 the rotamers caused by the hind...

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Detalles Bibliográficos
Autores principales: Popa, Marcel Mirel, Shova, Sergiu, Hrubaru, Madalina, Barbu, Loredana, Draghici, Constantin, Dumitrascu, Florea, Dumitrescu, Denisa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052417/
https://www.ncbi.nlm.nih.gov/pubmed/35493656
http://dx.doi.org/10.1039/d0ra02368j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052417/
https://www.ncbi.nlm.nih.gov/pubmed/35493656
http://dx.doi.org/10.1039/d0ra02368j

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