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Distinct clinical and somatic mutational features of breast tumors with high-, low-, or non-expressing human epidermal growth factor receptor 2 status

BACKGROUND: HER2-low breast cancers were reported to have distinct clinicopathological characteristics from HER2-zero; however, the difference in their genetic features remains unclear. This study investigated the clinical and molecular features of breast tumors according to HER2 status. METHODS: We...

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Detalles Bibliográficos
Autores principales: Zhang, Guochun, Ren, Chongyang, Li, Cheukfai, Wang, Yulei, Chen, Bo, Wen, Lingzhu, Jia, Minghan, Li, Kai, Mok, Hsiaopei, Cao, Li, Chen, Xiaoqing, Lin, Jiali, Wei, Guangnan, Li, Yingzhi, Zhang, Yuchen, Balch, Charles M., Liao, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052533/
https://www.ncbi.nlm.nih.gov/pubmed/35484593
http://dx.doi.org/10.1186/s12916-022-02346-9