Macrophage-based delivery of interleukin-13 improves functional and histopathological outcomes following spinal cord injury

BACKGROUND: Spinal cord injury (SCI) elicits a robust neuroinflammatory reaction which, in turn, exacerbates the initial mechanical damage. Pivotal players orchestrating this response are macrophages (Mφs) and microglia. After SCI, the inflammatory environment is dominated by pro-inflammatory Mφs/mi...

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Detalles Bibliográficos
Autores principales: Van Broeckhoven, Jana, Erens, Céline, Sommer, Daniela, Scheijen, Elle, Sanchez, Selien, Vidal, Pia M., Dooley, Dearbhaile, Van Breedam, Elise, Quarta, Alessandra, Ponsaerts, Peter, Hendrix, Sven, Lemmens, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052547/
https://www.ncbi.nlm.nih.gov/pubmed/35488301
http://dx.doi.org/10.1186/s12974-022-02458-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052547/
https://www.ncbi.nlm.nih.gov/pubmed/35488301
http://dx.doi.org/10.1186/s12974-022-02458-2

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