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Macrophage-based delivery of interleukin-13 improves functional and histopathological outcomes following spinal cord injury
BACKGROUND: Spinal cord injury (SCI) elicits a robust neuroinflammatory reaction which, in turn, exacerbates the initial mechanical damage. Pivotal players orchestrating this response are macrophages (Mφs) and microglia. After SCI, the inflammatory environment is dominated by pro-inflammatory Mφs/mi...
Autores principales: | Van Broeckhoven, Jana, Erens, Céline, Sommer, Daniela, Scheijen, Elle, Sanchez, Selien, Vidal, Pia M., Dooley, Dearbhaile, Van Breedam, Elise, Quarta, Alessandra, Ponsaerts, Peter, Hendrix, Sven, Lemmens, Stefanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052547/ https://www.ncbi.nlm.nih.gov/pubmed/35488301 http://dx.doi.org/10.1186/s12974-022-02458-2 |
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