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Elevation of α-1,3 fucosylation promotes the binding ability of TNFR1 to TNF-α and contributes to osteoarthritic cartilage destruction and apoptosis

BACKGROUND: Osteoarthritis (OA) is the most common form of arthritis and is characterized by the degradation of articular cartilage and inflammation of the synovial membrane. Fucosylation is an important feature of protein N/O-glycosylation and is involved in a variety of pathological processes, inc...

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Detalles Bibliográficos
Autores principales: Yu, Hanjie, Li, Mingxiu, Wen, Xiaodong, Yang, Jie, Liang, Xiaojun, Li, Xia, Bao, Xiaojuan, Shu, Jian, Ren, Xiameng, Chen, Wentian, Li, Zheng, Li, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052622/
https://www.ncbi.nlm.nih.gov/pubmed/35488351
http://dx.doi.org/10.1186/s13075-022-02776-z